HuffPost has a solid anaylsis (and not the only one I’ve seen) correctly noting that Majority Leader Mitch McConnell is no Senate mastermind. He is a masterful obstructionist, but has not delivered any strategic successes on legislation. This will be a weakness that the Democrats can exploit, as Mitch cannot be an obstructionist if he is the man in charge. Unless he were to oppose the President, which seems unlikely.
The Trumpcare Fight Shows Mitch McConnell Knows Just How Overrated He Is
http://www.huffingtonpost.com/entry/mitch-mcconnell-trumpcare-legacy_us_5953fd6be4b0da2c7320be69